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Transforming growth factor-beta facilitates breast carcinoma metastasis by promoting tumor cell survival

✍ Scribed by Qin Yu; Ivan Stamenkovic


Book ID
111577286
Publisher
Springer
Year
2004
Tongue
English
Weight
484 KB
Volume
21
Category
Article
ISSN
0262-0898

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## Abstract Transforming growth factor‐beta (TGF‐β), a potent inhibitor of normal melanocyte growth, does not significantly suppress growth of melanoma cells. The mechanism of melanocyte desensitization to TGF‐β in the transformation process remains largerly unknown. We investigated whether the tum