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Transforming growth factor beta 1 (TGF-β1) and rapamycin synergize to effectively suppress human T cell responses via upregulation of FoxP3+ Tregs

✍ Scribed by Koichi Kawamoto; Anil Pahuja; Bernhard J. Hering; Pratima Bansal-Pakala


Book ID
116940272
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
508 KB
Volume
23
Category
Article
ISSN
0966-3274

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The relationship between the expression of selected oncogenes having different modes of action and the loss of the capacity t o respond in vitro to transforming growth factor+ I (TGF-P I) was analyzed in human mammary epithelial cells (MEC). Primary MEC cultures from healthy donors and the spontaneo