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Transforming Growth Factor-Beta 1 Gene Polymorphisms and Expression in the Blood of Prostate Cancer Patients

✍ Scribed by Faria, Paula Cristina; Saba, Karla; Neves, Adriana Freitas; Cordeiro, Elisangela Rosa; Marangoni, Karina; Freitas, Danielo Garcia; Goulart, Luiz Ricardo

Book ID
111981625
Publisher
Informa plc
Year
2007
Tongue
English
Weight
589 KB
Volume
25
Category
Article
ISSN
0735-7907

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## Abstract Transforming growth factor Ξ²1 (TGFB1) acts as a growth inhibitor of normal colonic epithelial cells, however, as a tumor promoter of colorectal cancer (CRC) cells. To explore the association between genetic polymorphisms in the TGFB1 pathway and CRC susceptibility and clinical outcome,