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Transformed steroids 188. Synthesis routes for 11Β-hydroxy-substituted 16-dehydro-, 17Β-hydroxy- and 16α, 17α,-epoxypregnanes based on 17α-ethynyl-11Β-dihydroxyandrostanes

✍ Scribed by A. M. Turuta; T. M. Fadeeva; A. V. Kamernitskii


Book ID
112405485
Publisher
Springer
Year
1992
Tongue
English
Weight
457 KB
Volume
26
Category
Article
ISSN
0091-150X

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Synthesis and crystal structure of (22 R
✍ Csöregh, I.; Thalén, A.; Wickström, L.-I. 📂 Article 📅 1999 🏛 Oldenbourg Wissenschaftsverlag 🌐 English ⚖ 935 KB

## Abstract The 21-palmitate of the stereochemically pure glucocorticosteroid rofleponide [(22__R__)-6__α__,9__α__-difluoro-11__β__,21-dihydroxy-16__α__,17__α__-propylmethylenedioxypregn-4-ene-3,20-dione], C~41~H~64~O~7~F~2~, was synthesised, and its solid-state conformation and absolute configurat