Transformed NIH 3T3 cells expressing human melanoma N-ras oncogene metastasize to lymph node in nude mice

Recessive (mediator−) revertants from c-

Recessive (mediator−) revertants from c-h-ras oncogene-transformed NIH 3T3 cells: Tumorigenicity in nude mice and transient anchorage and serum independence of the recovered tumor cells in culture

✍ Toshiko Omata-Yamada; Hisafumi Yamada; Peter Lengyel 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 945 KB

## Abstract We have reported earlier the isolation of two recessive, serum‐ and anchoragedependent revertants (R116 and R260) from a c‐H‐ras oncogene‐transformed NIH 3T3 line. In both revertants, the oncogene was fully expressed and fusion of either revertant with (untransformed) NIH 3T3 cells, or