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Transformations of schiff bases derived from quinoline-8-carbaldehyde. Synthesis of C-8 substituted quinolines
✍ Scribed by Nüket Ocal; ÇIgdem Yolaçan; ŞEniz Kaban; Vargas M. Leonor; Vladimir Kouznetsov
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2001
- Tongue
- English
- Weight
- 57 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
The Schiff bases derived from quinoline‐8‐carbaldehyde and substituted aromatic amines were used in the synthesis of C‐8 substituted quinolines. 3‐Aryl‐2‐(8‐quinolinyl)‐4‐thiazolidinones were prepared from obtained aldimines by means of the cyclocondensation of mercapto acids. A series of 4‐N‐arylamino‐4‐(8‐quinolinyl)‐1‐butenes was synthesized through the addition of the Grignard reagent (allylmagnesium bromide) to the double bond C=N of these aldimines. The structure of the prepared compounds was established on the basis of their elemental analyses and spectral data.
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