Transformations of diaziridines and their fused analogues induced by electrophilic reagents
β Scribed by Makhova, Nina N; Shevtsov, Alexander V; Petukhova, Vera Yu
- Book ID
- 119996017
- Publisher
- Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 570 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0036-021X
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π SIMILAR VOLUMES
## It was found that a cleavage of the N-C bonds of C-mono-and C, C-disubstituted methylenediamino groups of 1,3-diazaadamantanes takes place by the action of electrophilic reagents. Data are given in the literature on the cleavage of N-C bonds of the methylenediamino group of 1,3-diazaadamantane
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proteolysis of ingested hemoglobin, is toxic to the parasite, but is normally removed by enzyme-catalyzed oxidative polymerization to hemozoin [3]. We speculated that 1 and 2 could interrupt this detoxification process by transferring an 0-atom to heme to create an iron-oxene intermediate or oxyheme