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Transformation to senescence with plasmid like DNA in the ascomycetePodospora anserina

✍ Scribed by P. Tudzynski; U. Stahl; K. Esser

Publisher: Springer-Verlag
Year: 1980
Tongue: English
Weight: 357 KB
Volume: 2
Category: Article
ISSN: 0172-8083
DOI: 10.1007/bf00435683

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✦ Synopsis

In the ascomycete Podospora anserina senescence through strain aging is under nucleo-cytoplasmic control and inducible in juvenile mycelia by an 'infective principle' transferred after cytoplasmic contact via anastomoses. A specific DNA called plasmid-like (pl) DNA, present exclusively in aging mycelia, was found to be identical with this 'infective principle', since it was possible to transform juvenile protoplasts to senescence by using purified p1DNA. Therefore a specific function may be attributed to this ccc DNA. Its direct involvement in a genetically programed senescence is confirmed and its development as a vector for transfer of genetic information in eukaryotes can be undertaken.

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