Methyl tertiary-butyl ether (MTBE) is an oxygenate that is added to gasoline to boost octane and enhance combustion, thereby reducing carbon monoxide and hydrocarbon tailpipe emissions. The acute and subchronic neurotoxicity of MTBE were evaluated in rats using a functional observation battery (FOB)
Transformation of tertiary butyl mercaptan in aerobic environments
โ Scribed by Kalainesan, S. ;Erickson, L.E. ;Hutchinson, S.L.L. ;Urban, J.E. ;Karthikeyan, R.
- Publisher
- American Institute of Chemical Engineers
- Year
- 2006
- Tongue
- English
- Weight
- 177 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0278-4491
- DOI
- 10.1002/ep.10136
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Methyl tertiary-butyl ether (MTBE) is one of the highest production volume chemicals in the USA. Previous results from in vitro genetic toxicity studies suggested that it was not mutagenic. However, chronic exposure at high levels resulted in liver tumors in female mice and kidney tumors in male rat
A two-generation reproductive toxicity study of methyl tertiary-butyl ether (MTBE) was conducted in Sprague-Dawley rats. Twenty-five rats of each sex (F 0 ) were exposed by inhalation to 0, 400, 3000 or 8000 ppm MTBE vapor, 6 h a day for 10 weeks prior to mating. Parental animals were then mated wit