Transformation of bone marrow-derived macrophages into ramified microglia during autoimmune inflammation of the axotomized rat facial nucleus

Transformation of donor-derived bone mar

Transformation of donor-derived bone marrow precursors into host microglia during autoimmune CNS inflammation and during the retrograde response to axotomy

✍ Alexander Flügel; Monika Bradl; Georg W. Kreutzberg; Manuel B. Graeber 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 768 KB

## Abstract Macrophages in the brain can have a triple source. They may originate from recently blood‐derived precursors, from the largely resident perivascular cell population (perivascular macrophages and related cells), and from intrinsic parenchymal as well as perivascular microglia. Although c