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Transformation of aminoethylisouronium salts. 1, S-aminoethylisothiouronium bromide hydrobromide- 14C

✍ Scribed by L. Kronrád; I. Kozák

Publisher
John Wiley and Sons
Year
1973
Tongue
French
Weight
210 KB
Volume
9
Category
Article
ISSN
0022-2135

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✦ Synopsis

INTROW

CT ION S-aminoethylisothiouronium salts (AET) are considered to be the m a t efficient radioprotective substances (1.2). They are relatively unstable in aqueous solutions where they are transformed .to 2-aminothiazolines (2-AT) (3-6). These substances are more toxic and their radioprotective effect is considerably lover than that of AET (7.8). From this point of view it is important to know the mechanism of the transformation of AET to their derivatives. The kinetics of the formation of 2-AT and mercaptoethylguanidine (MEG) in aqueous solutions of AET has been studied by Bitny-Slach-to (9).

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