Cell death in bioreactors: A role for ap
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R. P. Singh; M. Al.-Rubeai; C. D. Gregory; A. N. Emery
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Article
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1994
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John Wiley and Sons
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English
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The incidence of apoptotic and necrotic cell death was compared in CHO, SF9 insect cells, and murine plasmacytoma (J558L) and hybridoma (TB/C3) cells during in vitro cultivation in batch cultures. Acridine orange staining and fluorescence microscopy enabled the visualization of a classic morphologic