Transferrin subtypes in cystic fibrosis
โ Scribed by V. L. Pascali; E. Bravo; P. Auconi; D. Rastelli; S. Quattrucci; S. Perticarini; M. Antonelli
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 225 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
โฆ Synopsis
The molecular polymorphism and quantitative data of serum transferrin (Tf) were ascertained in a group of fibrocystic patients, their parents and controls. Quantitative rates of pre-albumin, retinol binding globulin (RBG) and alpha-1-glycoprotein were also investigated as a reference for the evaluation of Tf quantitative data. Neither different allele distributions nor abnormal electrophoretic patterns were observed among CF patients. A slight lowering of Tf, pre-albumin and RBG, probably due to malnutritional condition in CF subjects was found.
๐ SIMILAR VOLUMES
A 17-year-old boy and a 12-year-old girl with cystic fibrosis (forced expiratory volume in 1 sec, 36% and 14% of predicted values, respectively) developed severe right-sided lung infections with abscess formations and complete atelectases unresponsive to medical therapy. In both patients, unilateral
Complement components C3, C4, and C3A were estimated in 30 patients with cystic fibrosis aged 1 to 21 years (M:F = 16:14) and were compared with results in 40 healthy, age-matched subjects. The influences of the clinical score, sputum microbiology, and the patients' sex were also investigated. In co