The perfusion of rat brain with '251-transferrin resulted in a receptor-mediated uptake of transferrin into the endothelium of the blood-brain barrier followed by its detection in the brain. During a pulsechase experiment, lZSI-transferrin accumulated in the endothelial cells during the pulse, with
Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB)
✍ Scribed by Karsten Ulbrich; Telli Hekmatara; Elisabeth Herbert; Jörg Kreuter
- Book ID
- 116438079
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 415 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0939-6411
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