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Transfer of Retinol from Parenchymal to Stellate Cells in Liver is Mediated by Retinol-Binding Protein

✍ Scribed by Rune Blomhoff, Trond Berg and Kaare R. Norum


Book ID
123635552
Publisher
National Academy of Sciences
Year
1988
Tongue
English
Weight
569 KB
Volume
85
Category
Article
ISSN
0027-8424

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The synthetic retinoid 4-HPR has been shown to markedly lower the plasma concentration of both retinol and RBP in rats and humans. We have studied the effect of 4-HPR on the secretion of retinol-RBP from liver cells in vivo and in vitro. In rats maintained with a normal diet, a vitamin A-deficient d