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Transfection of SSTR-1 and SSTR-2 Inhibits Panc-1 Cell Proliferation and Renders Panc-1 Cells Responsive to Somatostatin Analogue

✍ Scribed by Min Li; Rongxin Zhang; Fei Li; Hao Wang; Hee Joon Kim; Lauren Becnel; Qizhi Yao; Changyi Chen; William E. Fisher


Book ID
118468906
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
205 KB
Volume
201
Category
Article
ISSN
1072-7515

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## Abstract PANC‐1 cells express proteinase‐activated receptors (PARs)‐1, ‐2, and respond to their activation by transient elevation of cytosolic [Ca^2+^] and accelerated aggregation (Wei et al., 2006, J Cell Physiol 206:322–328). We studied the effect of plasminogen (PGN), an inactive precursor of