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Transfection of primary human nasal epithelial cells using a biodegradable poly (ester amine) based on polycaprolactone and polyethylenimine as a gene carrier

โœ Scribed by Choi, Min-Koo; Arote, Rohidas; Kim, Sun-Young; Chung, Suk-Jae; Shim, Chang-Koo; Cho, Chong-Su; Kim, Dae-Duk

Book ID
118118378
Publisher
Informa plc
Year
2007
Tongue
English
Weight
285 KB
Volume
15
Category
Article
ISSN
1061-186X

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## Abstract ## Background Polyethylenimine (PEI) vectors are widely used in gene delivery because of their high transfection efficiency owing to a unique proton sponge effect. An increase in molecular weight increases transfection efficiency, but simultaneously results in increased toxicity. There