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Transdermal delivery of levonorgestrel. VIII. Effect of enhancers on rat skin, hairless mouse skin, hairless guinea pig skin, and human skin

โœ Scribed by Catz, Paul; Friend, David R.


Book ID
122822433
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
889 KB
Volume
58
Category
Article
ISSN
0378-5173

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Controlled-release delivery of 6-beta-naltrexol (NTXOL), the major active metabolite of naltrexone, via a transdermal patch is desirable for treatment of alcoholism. Unfortunately, NTXOL does not diffuse across skin at a therapeutic rate. Therefore, the focus of this study was to evaluate microneedl