## Abstract The clinical impact of biotechnology has been constrained by the limitations of traditional hypodermic injection of biopharmaceuticals. Microneedle patches have been proposed as a minimally invasive alternative. In this study, the translation of a dissolving microneedle patch designed f
Transdermal Delivery of Human Growth Hormone Through RF-Microchannels
โ Scribed by Galit Levin; Amikam Gershonowitz; Hagit Sacks; Meir Stern; Amir Sherman; Sergey Rudaev; Inna Zivin; Moshe Phillip
- Publisher
- Springer US
- Year
- 2005
- Tongue
- English
- Weight
- 249 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0724-8741
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A 2% commercial solution formulation of 5-fluorouracil (5-FU) was significantly better at delivering 5-FU than either a 1% or 5% solution. Among single component suspension formulations the highest transderreal delivery was obtained from the vehicle in which 5-FU was least soluble, isopropyl myrista
The aim of this article is to prepare and characterize inhalable dry powders of recombinant human growth hormone (rhGH), and assess their efficacy for systemic delivery of the protein in rats. The powders were prepared by spray drying using dimethyl-b-cyclodextrin (DMbCD) at different molar ratios i