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Transdermal delivery of 5-fluorouracil (5-FU) through hairless mouse skin by 1-alkylaminocarbonyl-5-FU prodrugs: Physicochemical characterization of prodrugs and correlations with transdermal delivery

โœ Scribed by K.B. Sloan; J.J. Getz; H.D. Beall; R.J. Prankerd


Book ID
113366103
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
963 KB
Volume
93
Category
Article
ISSN
0378-5173

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Transdermal delivery of 5-fluorouracil t
โœ E. F. Sherertz; K. B. Sloan; R. G. McTiernan ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 646 KB

A 2% commercial solution formulation of 5-fluorouracil (5-FU) was significantly better at delivering 5-FU than either a 1% or 5% solution. Among single component suspension formulations the highest transderreal delivery was obtained from the vehicle in which 5-FU was least soluble, isopropyl myrista