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Transcriptomics: Unravelling the biology of transcription factors and chromatin remodelers during development and differentiation

✍ Scribed by Gerard L. Brien; Adrian P. Bracken


Book ID
116881506
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
677 KB
Volume
20
Category
Article
ISSN
1084-9521

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## Abstract We present a molecular model of eukaryotic gene transcription. For the β‐globin locus, we hypothesise that a transcription machine composed of multiple RNA polymerase II (PolII) assembles using the locus control region as a foundation. Transcription and locus remodelling can be achieved