Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson’s disease
✍ Scribed by D. C. Duke; L. B. Moran; M. E. Kalaitzakis; M. Deprez; D. T. Dexter; R. K. B. Pearce; M. B. Graeber
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 166 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1364-6745
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Several links exist between the two mechanisms of neuronal degeneration (i.e., oxygen radical production and mitochondrial damage) proposed to have a role in Parkinson's disease. Indeed, mitochondria are critical targets for the toxic injury induced by oxygen radicals, and experimental evidence sugg
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