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Transcriptional targeting of small interfering RNAs into cancer cells

✍ Scribed by Trang Huynh; Sébastien Wälchli; Mouldy Sioud

Book ID
111676323
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
690 KB
Volume
350
Category
Article
ISSN
0006-291X

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## Abstract Survivin is a member of the inhibitor of apoptosis protein (IAP) family that is specifically overexpressed in cancer tissues. p53 is one of the tumor suppressor genes; its induction in response to DNA damage causes apoptosis and correlates with drug sensitivity. To investigate the possi