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Transcriptional repression of cyclin-dependent kinase inhibitor p21 gene by phospholipase D1 and D2

✍ Scribed by Hyun Jin Kwun; Jae Hwa Lee; Do Sik Min; Kyung Lib Jang


Book ID
117105406
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
459 KB
Volume
544
Category
Article
ISSN
0014-5793

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## Abstract The p27^Kip1^ (p27) cyclin‐dependent kinase inhibitor and c‐Myc oncoprotein play essential roles in control of cell cycle progression and apoptosis. Induction of __p27__ (__CDKN1B__) gene transcription by Forkhead box O proteins such as FOXO3a leads to growth arrest and apoptosis. Previ