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Transcriptional regulation of the ratMrp3gene promoter by the specificity protein (Sp) family members and CCAAT/enhancer binding proteins

โœ Scribed by Shwu-Jen Tzeng; Wen-Chang Chang; Jin-ding Huang

Publisher
BioMed Central
Year
2005
Tongue
English
Weight
782 KB
Volume
12
Category
Article
ISSN
1021-7770

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## Abstract Myelin basic protein (MBP) is one of the major components of the myelin sheath that insulates axons. In the central nervous system, MBP is synthesized by differentiating oligodendrocytes. The expression of MBP in oligodendrocytes is regulated mainly at the transcriptional level. The Sp1