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Transcriptional regulation of the NKT cell lineage

✍ Scribed by Constantinides, Michael G; Bendelac, Albert


Book ID
120937458
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
360 KB
Volume
25
Category
Article
ISSN
0952-7915

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Transcriptional regulation of lymphocyte
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The development of T cells and B cells from pluripotent hematopoietic precursors occurs through a stepwise narrowing of developmental potential that ends in lineage commitment. During this process, lineage-specific genes are activated asynchronously, and lineage-inappropriate genes, although initial