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Transcriptional regulation of the isocitrate lyase encoding gene in Saccharomyces cerevisiae

✍ Scribed by Ernestina Fernandez; Maria Fernandez; Fernando Moreno; Rosaura Rodicio


Book ID
115927825
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
529 KB
Volume
333
Category
Article
ISSN
0014-5793

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Structure and regulation of the isocitra
✍ A. SchΓΆler; H. -J. SchΓΌller πŸ“‚ Article πŸ“… 1993 πŸ› Springer-Verlag 🌐 English βš– 914 KB

The ICL1 gene encoding the isocitrate lyase from Saccharomyces cerevisiae was cloned and sequenced. A reading frame of 557 amino acids showing significant similarity to isocitrate lyases from seven other species could be identified. Construction of icl1 null mutants led to growth defects on C2 carbo