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Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors

✍ Scribed by Inês Milagre; Maria João Nunes; Maria João Gama; Rui Fernando Silva; Jean Marc Pascussi; Maria C. Lechner; Elsa Rodrigues


Book ID
111180924
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
942 KB
Volume
106
Category
Article
ISSN
0022-3042

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✍ Alia Al-Sarraj; Regina M. Day; Gerald Thiel 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB

## Abstract The transcription factors Sp1, Sp3, and Egr‐1 bind with their zinc finger DNA‐binding domains to GC‐rich sequences in the regulatory regions of their target genes. The similarity of the DNA‐binding sites of Sp1, Sp3, and Egr‐1 has triggered the hypothesis that they compete for the same