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Transcriptional regulation of the Drosophila segmentation gene fushi tarazu (ftz)

✍ Scribed by Charles R. Dearolf; Joanne Topol; Carl S. Parker

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 644 KB
Volume: 12
Category: Article
ISSN: 0265-9247
DOI: 10.1002/bies.950120303

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✦ Synopsis

ftz is one of the 'pair rule' segmentation genes of Drosophila melanogaster, and is an important component of the segmentation process in the fruit fly. We discuss the transcriptional mechanism which causes ftz to be expressed in a seven stripe pattern during embryogenesis.

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## Abstract Summary: The __Drosophila fushi tarazu__ (__ftz__) mRNA is one of the shortest‐lived metazoan mRNAs, and its instability is crucial for proper development of the embryo. Previously, we identified two cis‐acting elements that are required for __ftz__ mRNA degradation, one within the 5′ o