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TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION

โœ Scribed by Kuo, Chay T.; Leiden, Jeffrey M.


Book ID
120494376
Publisher
Annual Reviews
Year
1999
Tongue
English
Weight
280 KB
Volume
17
Category
Article
ISSN
0732-0582

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Transcriptional regulation of lymphocyte
โœ Ellen V. Rothenberg; Janice C. Telfer; Michele K. Anderson ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 247 KB ๐Ÿ‘ 1 views

The development of T cells and B cells from pluripotent hematopoietic precursors occurs through a stepwise narrowing of developmental potential that ends in lineage commitment. During this process, lineage-specific genes are activated asynchronously, and lineage-inappropriate genes, although initial