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Transcriptional regulation of macrophage arginase 1 expression and its role in atherosclerosis

✍ Scribed by Pourcet, Benoit; Pineda-Torra, Inés

Book ID
122371537
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
590 KB
Volume
23
Category
Article
ISSN
1050-1738

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## Abstract The aim of the current study was to investigate the cAMP‐dependent regulation of arginase‐1 (ARG1) expression in RAW‐macrophages. Basal ARG1 mRNA expression was low and increased upon incubation with the cAMP analogue Br‐cAMP. We used selective agonists of protein kinase A type I (PKAI)