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Transcriptional regulation of human CC chemokine CCL15 gene by NF-κB and AP-1 elements in PMA-stimulated U937 monocytoid cells

✍ Scribed by Yong-Hyun Shin; Kyung-No Son; Guy Wilhem Lee; Byoung S. Kwon; Jiyoung Kim

Book ID: 113485443
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 223 KB
Volume: 1732
Category: Article
ISSN: 0167-4781
DOI: 10.1016/j.bbaexp.2005.11.001

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## Abstract We have shown that the bacterial iron chelator, deferoxamine (DFO), triggers inflammatory signals including the production of CXC chemokine IL‐8, in human intestinal epithelial cells (IECs) by activating the ERK1/2 and p38 kinase pathways. In this study we investigated the mechanisms in