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Transcriptional Regulation of Human Adrenomedullin Gene in Vascular Endothelial Cells

✍ Scribed by Toshihiko Ishimitsu; Atsuro Miyata; Hiroaki Matsuoka; Kenji Kangawa

Book ID
115581626
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
387 KB
Volume
243
Category
Article
ISSN
0006-291X

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Vascular endothelial cells are potent modulators of vascular tone in response to shear stress. Levels of vasoactive peptides such as adrenomedullin (AM), endothelin-1 (ET-1), C-type natriuretic peptide (CNP), and nitric oxide (NO) are affected by fluid shear stress. AM, a potent vasodilator and supp