Transcriptional regulation of gene expression by the coding sequence: An attempt to enhance expression of human AChE

Differential regulation of c-fos express

Differential regulation of c-fos expression in estrogen-induced hamster renal tumors compared with kidney not due to creation of an estrogen-response element by point mutation in the gene's flanking sequence

✍ Stephen F. Sarabia; Joachim G. Liehr 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB 👁 1 views

The conversion of a palindromic sequence, GGTCTnnnAGACC, in the 5′-flanking region of the murine c-fos proto-oncogene into a functional estrogen-response element by a single base change into GGTC A / G nnnAGACC has previously been postulated [Nawaz et al., 1993] as a possible mechanism of the induct