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Transcriptional regulation of farnesyl pyrophosphate synthase by liver X receptors

✍ Scribed by Junichi Fukuchi; Ching Song; Andrew L. Ko; Shutsung Liao

Book ID
117213641
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
186 KB
Volume
68
Category
Article
ISSN
0039-128X

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Organic anion transporting polypeptide 1B1 (OATP1B1) is a liver-enriched transporter involved in the hepatocellular uptake of many endogenous molecules and several structurally divergent drugs in clinical use. Although OATP1B1 coding region polymorphisms are known to make an impact on substrate drug