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Transcriptional regulation of cytochrome P-450 aromatase gene (CYP19) in human osteoblasts in primary cultures

✍ Scribed by A Enjuanes; A Supervı́a; D Grinberg; S Balcells; L Mellibovsky; X Nogués; S Serrano; J Carbonell; A Dı́ez

Book ID
117807432
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
24 KB
Volume
29
Category
Article
ISSN
8756-3282

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## Abstract Cytochrome P450 aromatase (CYP19) is the terminal enzyme in the steroidogenic pathway that converts androgens (e.g., testosterone) into estrogens (e.g., estradiol). Regulation of this gene dictates the ratio of androgens to estrogens; therefore, appropriate expression of this enzyme is