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Transcriptional regulation of apolipoprotein E expression by cyclic AMP

✍ Scribed by Marise Andreani-Mangeney; Yves Vandenbrouck; Brigitte Janvier; Delphine Girlich; Gilbert Bereziat

Book ID
117106711
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
544 KB
Volume
397
Category
Article
ISSN
0014-5793

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The treatment of rat glioma C6 cells with 10 pM isoproterenol (Ipt) for 4 days upregulated the expression of the myelin-associated glycoprotein (MAG) gene by approximately 55-fold over the control value. The constant presence of Ipt in the medium was required for the maximal upregulation, as time-re