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Transcriptional Regulation: Lessons from the Human Neurotropic Polyomavirus, JCV

✍ Scribed by GANESH V. RAJ; KAMEL KHALILI


Book ID
112270139
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
143 KB
Volume
213
Category
Article
ISSN
0042-6822

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Transgenic mice harboring the early genome from the human neurotropic JC virus, JCV, develop massive abdominal tumors of neural crest origin during 6-8 months after birth and succumb to death a few weeks later. The viral early protein, T-antigen, which possesses the ability to transform cells of neu