Transcriptional mechanism of suppression of insulin gene expression by AMP-activated protein kinase activator 5-amino-4-imidazolecarboxamide riboside (AICAR) in β-cells
✍ Scribed by Ji-Won Kim; Jae-Hyoung Cho; Seung-Hyun Ko; Heon-seok Park; Joohun Ha; Ki-Ho Song; Ho-Young Son; Sung-Soo Kim; Kun-Ho Yoon; Haeyoung Suh-Kim
- Book ID
- 116295982
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 625 KB
- Volume
- 365
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Recent studies suggest AMP‐activated protein kinase (AMPK), an enzyme involved in energy homeostasis, might be a novel signaling pathway in regulating inflammatory response, but the precise intracellular mechanisms are not fully understood. In this study, we have demonstrated that 5‐ami
Multidrug resistance (MDR) is a major obstacle in cancer chemotherapy and its inhibition is an effective way to reverse cancer drug resistance. In the present study, we investigated that puerarin, a natural isoflavonoid from Pueraria lobata, down-regulated MDR1 expression in MCF-7/adriamycin (MCF-7/