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Transcriptional Dysregulation in Alzheimer's disease

✍ Scribed by Paudel, Hemant; Lu, Yifan; MacDonald, Ryen

Book ID
121945694
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
49 KB
Volume
7
Category
Article
ISSN
1552-5260

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Transcription factor Sp1 dysregulation i
Transcription factor Sp1 dysregulation in Alzheimer's disease
✍ Bruce A. Citron; John S. Dennis; Ross S. Zeitlin; Valentina Echeverria πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 155 KB πŸ‘ 1 views

## Abstract Altered gene expression occurs in central nervous system disorders, including Alzheimer's disease (AD). Transcription factor Sp1 may be involved insofar as it can regulate the expression of several AD‐related proteins, including amyloid precursor protein (APP) and tau. Sp1 could itself