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Transcriptional control of the murine CD21 gene can be influenced by histone acetylation

โœ Scribed by M. Zabel; H. Hu; J.J. Weis; J.H. Weis


Book ID
117326536
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
298 KB
Volume
35
Category
Article
ISSN
0161-5890

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## Abstract Butyric acid is well recognized as a histone deacetylase (HDAC) inhibitor, and changes in histone acetylation are thought to alter gene expression. The mechanism by which sodium butyrate (NaB) induces p21^WAF1/CIP1^, a critical gene involved in the antiproliferative effect of NaB, was s