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Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts

โœ Scribed by Mark A. Casillas; Nadejda Lopatina; Lucy G. Andrews; Trygve O. Tollefsbol


Book ID
111551552
Publisher
Springer
Year
2003
Tongue
English
Weight
273 KB
Volume
252
Category
Article
ISSN
0300-8177

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โœ Chuanzhong Mei; Lidong Sun; Yonglei Liu; Yong Yang; Xiumei Cai; Mingzhu Liu; Wan ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 394 KB

## Abstract DNA methyltransferases (DNMTs) are essential for maintenance of aberrant methylation in cancer cells and play important roles in the development of cancers. Unregulated activation of PI3K/Akt pathway is a prominent feature of many human cancers including human hepatocellular carcinoma (