A key event in the regulation of eukaryotic gene expression is the posttranslational modification of nucleosomal histones, which converts regions of chromosomes into transcriptionally active or inactive chromatin. The most well studied posttranslational modification of histones is the acetylation of
β¦ LIBER β¦
Transcriptional control: Calling in histone deacetylase
β Scribed by Astrid Kiermaier; Martin Eilers
- Book ID
- 114320268
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 405 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0960-9822
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## Abstract Skeletogenesis occurs continuously during the lifespan of vertebrate organisms. In development, the skeleton is patterned and modeled until each bone achieves its optimal shape and full size. During adults, the skeleton is remodeled to maintain strength and release calcium. The boneβres