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Transcriptional activation of the utrophin promoter B by a constitutively active Ets-transcription factor

✍ Scribed by Alexandre Briguet; Dorothee Bleckmann; Mickaël Bettan; Nicolas Mermod; Thomas Meier

Book ID
117669688
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
279 KB
Volume
13
Category
Article
ISSN
0960-8966

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Overexpression of the HER2/Neu receptor is correlated to a poor prognosis in tumor patients and leads to stimulation of mitogen-activated protein kinase (MAPK) signaling pathways, which in turn activate transcription factors, such as the ETS protein ER81. Here, we have analyzed whether, on the other