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Transcriptional activation of Cidec by PPARγ2 in adipocyte

✍ Scribed by Yoon-Jin Kim; Si Young Cho; Cheol Hee Yun; Yang Soo Moon; Tae Ryong Lee; Sang Hoon Kim

Book ID: 116297527
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 485 KB
Volume: 377
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2008.09.129

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## Abstract Germline mutations in the tumor suppressor gene __PTEN__ (protein phosphatase and tensin homolog located on chromosome ten) predispose to heritable breast cancer. The transcription factor PPARγ has also been implicated as a tumor suppressor pertinent to a range of neoplasias, including