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Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-λ, ε and ζ

✍ Scribed by Kampfer, Sonja; Hellbert, Karina; Villunger, Andreas; Doppler, Wolfgang; Baier, Gottfried; Grunicke, Hans H.; Überall, Florian


Book ID
111745529
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
398 KB
Volume
17
Category
Article
ISSN
0261-4189

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## Abstract Spontaneously immortalized human mammary epithelial cells MCF‐IOA were transfected with an activated c‐Ha‐ras oncogene. Transfected cells (MCF‐IOT) acquire a malignant pheno‐type, as already reported. Studies of l‐2′‐deoxyuridine incorporation in cultures given graded doses of hydrocort