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Transcription of the human U2 snRNA genes continues beyond the 3′ box in vivo

✍ Scribed by Cuello, Paula; Boyd, Diana C.; Dye, Michael J.; Proudfoot, Nick J.; Murphy, Shona

Book ID
111745992
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
281 KB
Volume
18
Category
Article
ISSN
0261-4189

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The multicopy human U2 small nuclear (sn)RNA genes are transcribed by RNA polymerase (pol) II and contain two major promoter elements upstream of the transcription start site: an essential proximal sequence element (PSE) at around À55 and a distal sequence element (DSE) at around À220. We have carri