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Transcription of Cytokeratins 8, 18, and 19 in Bone Marrow and Limited Expression of Cytokeratins 7 and 20 by Carcinoma Cells: Inherent Limitations for RT-PCR in the Detection of Isolated Tumor Cells

✍ Scribed by Dimmler, Arno; Gerhards, Roswitha; Betz, Christoph; Günther, Klaus; Reingruber, Bertram; Horbach, Thomas; Baumann, Irith; Kirchner, Thomas; Hohenberger, Werner; Papadopoulos, Thomas

Book ID: 109886382
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 691 KB
Volume: 81
Category: Article
ISSN: 0023-6837
DOI: 10.1038/labinvest.3780349

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✍ Theresia Weber; Jeannine Lacroix; Stefan Wörner; Helgard Weckauf; Steffi Winkler 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 148 KB 👁 1 views

## Abstract Despite an extensive surgical approach only 50% of the patients with medullary thyroid carcinoma (MTC) are biochemically cured. The failure to cure a larger number of patients is a result of the early dissemination of MTC. The present study evaluates two RT‐PCR based assays for the dete