The identification of two transcription factors that, when mutated, are responsible for severe autoimmune disease in humans is leading to a better understanding of the fundamental processes involved in T-cell tolerance. Both AIRE and FOXP3, identified initially via their association with genetically
β¦ LIBER β¦
Transcription factors in the pathogenesis of autoimmunity
β Scribed by Stanford L Peng
- Book ID
- 116366107
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 324 KB
- Volume
- 110
- Category
- Article
- ISSN
- 1090-2341
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Expression of the jun family of transcription factorslproto-oncogenes in lung cancer From recent studies it is now clear that the product of the cellular counterpart of the oncogene jun (Maki et al., 1987) is one of the proteins making up the transcription-factor preparation AP-1 (Angel et al., 198