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Transcription elongation complex: structure and function

✍ Scribed by Nataliya Korzheva; Arkady Mustaev

Book ID
117764737
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
362 KB
Volume
4
Category
Article
ISSN
1369-5274

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## Abstract **Background:** The human Spt4/Spt5 complex, termed DRB‐sensitivity inducing factor (DSIF) is a dual regulator of transcription that stimulates, or, when cooperating with negative elongation factor (NELF), represses RNA polymerase II (RNAPII) elongation. Spt4 and Spt5 are also thought t